Lazio could potentially seal their place in the Champions League knockout rounds with a win in Tuesday's home fixture against Celtic.
Meanwhile, the Scottish champions are on the verge of an early exit after mustering just one point from their four group matches.
They looked set to enjoy a successful trip to Salerno when Ciro Immobile dispatched his 43rd-minute spot kick to become the first player to reach 100 away goals in Serie A.
However, Grigoris Kastanos pulled Salernitana level within 10 minutes of the restart, before former Lazio man Antonio Candreva netted the decisive goal to condemn the Biancocelesti to a sixth Serie A defeat of the season, extending their winless league run to three matches.
While their domestic campaign is proving to be a disappointment, Lazio are on the brink of reaching the knockout rounds of the Champions League after collecting seven points from their four group matches.
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